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The pancreas is a vital organ that produces enzymes to assist in food digestion and hormones such as insulin, which regulates blood sugar or glucose metabolism. Pancreatitis is inflammation of the pancreas. Common clinical signs include decreased appetite, nausea, vomiting, lethargy, diarrhea, and abdominal pain. Diagnosis is generally made with laboratory testing and/or abdominal ultrasound. Successful pancreatitis management will depend on early diagnosis and prompt medical therapy. The prognosis depends on the severity of the disease and the response to initial therapy.
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Pancreas-specific lipase is a form of lipase produced only in the pancreas and is highly specific to the pancreas. Blood values increase only when there is pancreatic inflammation. A version of the cPLI test can now be used in-clinic (SNAP fPL© from IDEXX). Ideally, the sample should also be sent to the laboratory to get an actual value of cPLI to help with treatment and monitoring.
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Panniculitis is a localized inflammation of the tissues under the skin, causing a firm swelling (nodule) that may ulcerate and drain fluid. It is a common problem in cats and is less common in dogs. There are several causes of panniculitis, but in younger animals with a single lump, the cause is often blunt trauma and, in cats, it is often caused by bite wounds from fighting. An accurate diagnosis relies on the microscopic examination of tissue and the most common treatment is the surgical removal of the lump(s).
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Chronic superficial keratitis (CSK), or pannus, is a potentially blinding disease affecting the cornea. Any dog breed can be affected by pannus, but it is predominantly seen in German shepherds, Belgian shepherds, and border collies. Diagnosis is based on medical history and clinical signs. Treatment involves using topical corticosteroids or other immune-modulating drugs. If diagnosed early and treatment plans are followed, many dogs can have a good prognosis and live a normal life.
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Panosteitis is a painful inflammation of the outer surface or shaft of one or more long bones of the legs. It is sometimes called growing pains. Panosteitis is a condition that affects young, rapidly growing dogs. Panosteitis will be suspected if the patient shows pain when pressure is applied to the affected bone(s). The diagnosis is confirmed by X-rays, which usually show a characteristic increase in the density of the affected bones. Although this disease will spontaneously resolve, during episodes of lameness the condition is very painful. At these times, treatment is supportive, using pain medication and anti-inflammatory drugs as needed.
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Papillomas are benign, sometimes multiple, tumors caused by viruses. They are commonly known as warts. The virus is transmitted through direct contact from an infected pet or the pet’s environment (e.g., toys, food bowls, or bedding) and gain access to the body when the skin becomes softened by moisture, through cuts and abrasions, or with the assistance of insects. Pets with immature immune systems such as young dogs and puppies, and those that are immune compromised, are more prone to developing papilloma tumors. The tumors often disappear within 1-2 months because the animal slowly develops an immunity to them. However, sometimes they persist, and surgical removal is necessary.
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Parvovirus may affect dogs of all ages but is most common in unvaccinated dogs less than one year of age. Young puppies under five months of age are usually the most severely affected and difficult to treat. Clinical signs can vary but generally include severe vomiting and diarrhea; the diarrhea often has a powerful smell, may contain lots of mucus, and may or may not contain blood. Most dogs with CPV infection recover if aggressive treatment is used and if therapy is started before severe septicemia and dehydration occur.
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Patent ductus arteriosus (PDA) is a heart defect that occurs when the ductus arteriosus (an opening between the aorta and the pulmonary artery) fails to close at birth. A PDA is usually diagnosed when your veterinarian hears a continuous heart murmur during a routine physical examination of your puppy. This article explains PDA and discusses signs, treatment, and prognosis for this condition.
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Pemphigus is an autoimmune skin disease in which the body's immune system attacks the connections between its own skin cells. The three most common types of pemphigus are pemphigus foliaceus, pemphigus vulgaris, and pemphigus erythematosus. Treatment requires suppression of the immune system and prognosis varies depending on the type.
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Perianal fistula, also known as anal furunculosis is a serious medical condition that most commonly affects German Shepherd dogs. Perianal fistulas are characterized by chronic, purulent, smelly, ulcerating, sinus tracts in the anal region and surrounding skin. More recent studies indicate that the condition is more likely caused by an autoimmune disease. Medical management with immune-modulating drugs is now the preferred therapy. In severe cases, surgery is required to debride or remove as much infected tissue as possible.
